Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578389 | 0.90 | LMNA (0.47) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL9979547 | 0.90 | LMNA (0.47) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL9979529 | 0.88 | LMNA (0.45) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL9979724 | 0.87 | ATM (0.52) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL9979682 | 0.87 | LMNA (0.49) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL9979541 | 0.87 | LMNA (0.44) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL13215978 | 0.86 | LMNA (0.43) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL14578270 | 0.85 | LMNA (0.43) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL9979590 | 0.85 | LMNA (0.46) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL13215923 | 0.84 | LMNA (0.42) | LMNAPOLBNTRK1CHRM3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |