Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979550 | 0.89 | ATM (0.55) | ATMNAMPTRAB9ASMN1; SMN2GAA | |
| SCHEMBL9979539 | 0.87 | ATM (0.53) | ATMNAMPTRAB9ASMN1; SMN2GAA | |
| SCHEMBL9979697 | 0.87 | LMNA (0.47) | ATMGAAALDH1A1LMNAMAPT | |
| SCHEMBL14578422 | 0.86 | ATM (0.51) | ATMNAMPTRAB9ASMN1; SMN2GAA | |
| SCHEMBL14266437 | 0.81 | ALDH1A1 (0.40) | RAB9ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1085423 | 0.81 | ATM (0.68) | ATMNAMPTRAB9ASMN1; SMN2GAA | |
| SCHEMBL14578360 | 0.79 | NTRK1 (0.40) | RAB9ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL12393705 | 0.79 | ATM (0.62) | ATMNAMPTRAB9ASMN1; SMN2GAA | |
| SCHEMBL646511 | 0.79 | ATM (0.62) | ATMNAMPTRAB9ASMN1; SMN2GAA | |
| SCHEMBL2354921 | 0.78 | ATM (0.61) | ATMNAMPTRAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |