Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979515 | 0.98 | PPARD (0.39) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL9979709 | 0.91 | PPARD (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL9979708 | 0.91 | PPARD (0.48) | ALDH1A1MAPTMEN1KMT2APPARD | |
| SCHEMBL9979707 | 0.90 | PPARD (0.48) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL9979608 | 0.90 | PPARD (0.50) | PPARDPPARGPPARAUGCG | |
| SCHEMBL9979513 | 0.89 | PPARD (0.48) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL9979580 | 0.80 | PKM (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9979706 | 0.79 | PPARD (0.60) | PPARDPPARGPPARA | |
| SCHEMBL9979506 | 0.79 | PPARD (0.62) | PPARDPPARGPPARA | |
| SCHEMBL9979632 | 0.77 | PPARD (0.60) | PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |