Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.39 |
| ▸ | UGCG | Q16739 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979629 | 0.85 | PPARD (0.41) | GRM1UGCG | |
| SCHEMBL9979708 | 0.82 | PPARD (0.48) | UGCGALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9979515 | 0.81 | PPARD (0.39) | PKMRAB9AUGCGCASP3KDM4E | |
| SCHEMBL9979712 | 0.80 | ALDH1A1 (0.40) | PKMRAB9AUGCGCASP3KDM4E | |
| SCHEMBL9979465 | 0.76 | NPC1 (0.59) | PKMNPC1RAB9AGRM1UGCG | |
| SCHEMBL9979657 | 0.75 | NPC1 (0.55) | PKMNPC1RAB9AGRM1UGCG | |
| SCHEMBL9979608 | 0.73 | PPARD (0.50) | UGCG | |
| SCHEMBL9979599 | 0.73 | NPC1 (0.55) | PKMNPC1RAB9AGRM1UGCG | |
| SCHEMBL9979506 | 0.72 | PPARD (0.62) | — | |
| SCHEMBL9979513 | 0.72 | PPARD (0.48) | PKMKDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |