Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222887 | 0.85 | F10 (0.69) | F10KLKB1NPC1RAB9ATP53 | |
| SCHEMBL9979791 | 0.81 | HDAC1 (0.63) | F10KLKB1NPC1RAB9ATP53 | |
| SCHEMBL205172 | 0.80 | PTPN11 (0.62) | F10KLKB1NPC1RAB9ATP53 | |
| SCHEMBL5221640 | 0.77 | F10 (0.81) | F10NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL5402070 | 0.76 | SMN1; SMN2 (0.58) | F10NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6935548 | 0.75 | ALDH1A1 (0.65) | F10NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL3275215 | 0.75 | ALDH1A1 (0.44) | NPC1RAB9AKMT2AALDH1A1MAOA | |
| SCHEMBL7249253 | 0.73 | F10 (0.69) | F10NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL3783197 | 0.72 | F10 (0.68) | F10KLKB1NPC1RAB9ATP53 | |
| SCHEMBL7242479 | 0.71 | TP53 (0.69) | F10NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | disclosed |