Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | F10 | P00742 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21870513 | 0.91 | ALDH1A1 (0.59) | ALDH1A1F10NPC1RAB9ATP53 | |
| SCHEMBL7249253 | 0.91 | F10 (0.69) | ALDH1A1F10NPC1RAB9ATP53 | |
| SCHEMBL15775332 | 0.87 | ALDH1A1 (0.55) | ALDH1A1F10NPC1RAB9ATP53 | |
| SCHEMBL31465694 | 0.84 | CES2 (0.55) | ALDH1A1F10NPC1RAB9ATP53 | |
| SCHEMBL9523014 | 0.82 | S1PR4 (0.69) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8832040 | 0.82 | F10 (0.81) | ALDH1A1F10NPC1RAB9ATP53 | |
| SCHEMBL9522743 | 0.81 | S1PR4 (0.58) | ALDH1A1NPC1RAB9ATP53KMT2A | |
| SCHEMBL4138460 | 0.80 | POLB (0.67) | NPC1RAB9ASMN1; SMN2KMT2AKCNK9 | |
| SCHEMBL5221661 | 0.80 | TP53 (0.62) | F10NPC1RAB9ATP53SMN1; SMN2 | |
| Ameltolide SCHEMBL635392 | 0.79 | S1PR4 (0.56) | ALDH1A1SMN1; SMN2KMT2APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279633-B1 | ANTICONVULSANT AGENTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | claimed |
| EP-0279633-A2 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1988-08-24 | — | — | EP | claimed |
| EP-1268051-A2 | DOSING FORM FOR REAGENTS, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND PRODUCTION OF SAID DOSING FORM | H. Lundbeck A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068599-A2 | DOSING FORM FOR REAGENTS, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND PRODUCTION OF SAID DOSING FORM | H. LUNDBECK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
| EP-0279633-B1 | ANTICONVULSANT AGENTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4981866-A | BENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4939163-A | 4-substituted benzamide derivatives | ELI LILLY AND COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4835181-A | Anticonvulsant agents using cyano dimethylphenyl benzamides | ELI LILLY AND COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0279633-A2 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |