Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979993 | 0.84 | FASN (0.42) | ESR2FASNCYP3A4CYP2C9APP | |
| SCHEMBL9763893 | 0.84 | ESR2 (0.50) | ESR2FASNHRH3NPC1RAB9A | |
| SCHEMBL4434770 | 0.84 | ESR2 (0.50) | ESR2FASNHRH3NPC1RAB9A | |
| SCHEMBL4432796 | 0.83 | ESR2 (0.49) | ESR2FASNHRH3NPC1RAB9A | |
| SCHEMBL20976648 | 0.82 | ESR2 (0.40) | ESR2FASNHRH3NPC1RAB9A | |
| SCHEMBL14206986 | 0.81 | ESR2 (0.47) | ESR2FASNHRH3NPC1RAB9A | |
| SCHEMBL4427660 | 0.81 | ESR2 (0.50) | ESR2FASNNPC1RAB9ACYP3A4 | |
| SCHEMBL4438458 | 0.80 | ESR2 (0.46) | ESR2FASNHRH3NPC1RAB9A | |
| SCHEMBL15172823 | 0.80 | ESR2 (0.46) | ESR2FASNHRH3NPC1RAB9A | |
| SCHEMBL12656041 | 0.80 | HDAC2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-20230323209-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| US-11760931-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11702597-B2 | Azo dye | MERCK PATENT GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11667841-B2 | Dibenzofuran and dibenzothiophene derivatives | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20180195002-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180142152-A1 | COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20170002269-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| US-20120256124-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-11 | — | — | US | disclosed |
| US-8168083-B2 | Electro-optical light control element, electro-optical display and control medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-7922934-B2 | s-Indacene and indeno[5,6-d][1,3]dioxol-derivatives and use thereof as components of liquid-crystal mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-04-12 | — | — | US | disclosed |
| WO-2010089092-A1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2010-08-12 | — | — | WO | disclosed |
| US-20100188630-A1 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100155662-A1 | S-INDACENE AND INDENO[5,6-D][1,3]DIOXOL-DERIVATIVES AND USE THEREOF AS COMPONENTS OF LIQUID-CRYSTAL MIXTURES | MERCK PATENT GESELLSCHAFT (DE) | 2010-06-24 | — | — | US | disclosed |
| US-7563491-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2009-07-21 | — | — | US | disclosed |
| US-7553522-B2 | LC-mixtures with low frequency dependence for TFT-displays | MERCK PATENT GMBH (DE) | 2009-06-30 | — | — | US | disclosed |
| US-7445819-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20070034829-A1 | liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667841-B2 | Dibenzofuran and dibenzothiophene derivatives | DDT, MYT1, DBF4 | ESR2 3924/4885FASN 3326/4885HRH3 3986/4885 |
| US-20100155662-A1 | S-INDACENE AND INDENO[5,6-D][1,3]DIOXOL-DERIVATIVES AND USE THEREOF AS COMPONENTS OF LIQUID-CRYSTAL MIXTURES | IPO5, SFXN3, SFXN1 | ESR2 2046/4885FASN 3556/4885HRH3 1744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.