Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980392 | 0.86 | MEN1 (0.51) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9980429 | 0.86 | GAA (0.54) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12067920 | 0.86 | MEN1 (0.49) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12065564 | 0.84 | MEN1 (0.49) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12066385 | 0.82 | MAPT (0.72) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9980483 | 0.81 | MEN1 (0.46) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9980390 | 0.81 | RAB9A (0.65) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1804039 | 0.79 | KDM4E (0.62) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12003698 | 0.77 | TNNI3K (0.48) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL12065555 | 0.77 | CA1 (0.48) | MEN1KMT2AGAAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |