Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29014480 | 0.88 | — | — | |
| SCHEMBL19838559 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL29144528 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL5652646 | 0.88 | — | — | |
| Oxirane SCHEMBL28467741 | 0.84 | — | — | |
| Formamide SCHEMBL28513591 | 0.79 | — | — | |
| Pyrimidine SCHEMBL28763829 | 0.75 | AURKA (0.37) | AURKAAURKBINCENP | |
| Bromobenzene SCHEMBL28859942 | 0.75 | ALDH1A1 (0.50) | AURKAAURKBINCENPFKBP5ALDH1A1 | |
| Maleic Acid SCHEMBL31158052 | 0.72 | MAPT (0.41) | AURKAAURKBINCENPHDAC8HDAC6 | |
| SCHEMBL28843930 | 0.72 | AURKA (0.34) | AURKAAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |