Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16120857 | 0.92 | AKT1 (0.53) | AKT1TDP1DRD2GAAALDH1A1 | |
| SCHEMBL20574342 | 0.92 | AKT1 (0.53) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL3154615 | 0.91 | TDP1 (0.51) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL22915492 | 0.90 | AKT1 (0.54) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL1449045 | 0.89 | TDP1 (0.54) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL22100919 | 0.89 | CA1 (0.51) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL17347403 | 0.89 | AKT1 (0.53) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL7801592 | 0.88 | TDP1 (0.56) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL17738032 | 0.88 | TDP1 (0.56) | AKT1TDP1DRD2MEN1GAA | |
| SCHEMBL28508194 | 0.88 | TDP1 (0.56) | AKT1TDP1DRD2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778653-B1 | NOVEL REACTIVE ALGINIC ACID DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2025-07-09 | — | — | EP | disclosed |
| CN-110914240-B | Norbornenone compounds releasing carbon monoxide | 奥塔哥创新有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2024-01-16 | — | — | US | disclosed |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2023-04-13 | — | — | US | disclosed |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2023-04-13 | — | — | US | disclosed |
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-02-23 | — | — | US | disclosed |
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-02-23 | — | — | US | disclosed |
| US-20050233462-A1 | Reagents and a method for saturation labelling of proteins | GLOBAL LIFE SCIENCES SOLUTIONS GERMANY GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
| US-20050208015-A1 | Glycerol derivative | TECNO NETWORK SHIKOKU CO., LTD (JP) | 2005-09-22 | — | — | US | disclosed |
| CN-1650168-A | Reagents and methods for saturation labelling of proteins | AMOSEN BIOLOG SCIENCE BRITISH (GB) | 2005-08-03 | — | — | CN | disclosed |
| EP-1550651-A1 | GLYCEROL DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-07-06 | — | — | EP | disclosed |
| EP-1520176-A1 | REAGENTS AND A METHOD FOR SATURATION LABELLING OF PROTEINS | Amersham Biosciences UK Limited (GB) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005933-A1 | REAGENTS AND A METHOD FOR SATURATION LABELLING OF PROTEINS | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2004-01-15 | — | — | WO | disclosed |
| EP-0429611-B1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-28 | — | — | EP | disclosed |
| US-5595741-A | Aminoalkylmaleimides and hapten and antigen derivatives derived therefrom as well as conjugates with peptides or proteins | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-21 | — | — | US | disclosed |
| US-5180816-A | One vial method for labeling protein/linker conjugates with technetium-99M | CENTOCOR (US) | 1993-01-19 | — | — | US | disclosed |
| US-5144043-A | Coupling protein or peptide to radionucleotide; labeling antibodies | CENTOCOR (US) | 1992-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | BTN3A1, ANTXR2, CLTA | AKT1 4224/4885TDP1 3065/4885DRD2 3485/4885 |
| US-20050233462-A1 | Reagents and a method for saturation labelling of proteins | SET, IK, MRPS22 | AKT1 3116/4885TDP1 4738/4885DRD2 2191/4885 |
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | AKT1 2227/4885TDP1 972/4885DRD2 1742/4885 |
| US-20050208015-A1 | Glycerol derivative | GK, GLS, GLS2 | AKT1 354/4885TDP1 1983/4885DRD2 2056/4885 |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | CD2BP2, EPCAM, CD74 | AKT1 3816/4885TDP1 2280/4885DRD2 4051/4885 |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | AKT1 986/4885TDP1 878/4885DRD2 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.