Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998261 | 0.92 | AKT1 (0.59) | AKT1IDO1DRD2CA12CA1 | |
| SCHEMBL9871339 | 0.85 | MGLL (0.51) | AKT1IDO1DRD2CA12CA1 | |
| SCHEMBL30756675 | 0.84 | MGLL (0.54) | AKT1IDO1DRD2CA12CA1 | |
| SCHEMBL16120857 | 0.84 | AKT1 (0.53) | AKT1DRD2CA1CA2TDP1 | |
| SCHEMBL12617467 | 0.84 | MGLL (0.54) | AKT1IDO1DRD2CA12CA1 | |
| SCHEMBL3154615 | 0.83 | TDP1 (0.51) | AKT1DRD2CA12CA1CA2 | |
| SCHEMBL22915492 | 0.82 | AKT1 (0.54) | AKT1DRD2MALT1TDP1ALDH1A1 | |
| SCHEMBL20500894 | 0.82 | MALT1 (0.51) | AKT1IDO1DRD2MALT1 | |
| SCHEMBL1449045 | 0.82 | TDP1 (0.54) | AKT1DRD2CA12CA1CA2 | |
| SCHEMBL22100919 | 0.82 | CA1 (0.51) | AKT1DRD2CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383846-B1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | OTAGO INNOVATION LTD (NZ) | 2022-06-22 | — | — | EP | disclosed |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | OTAGO INNOVATION LIMITED (NZ) | 2021-07-27 | — | — | US | disclosed |
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-04-09 | — | — | US | disclosed |
| US-20180346420-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | UNIVERSITY OF OTAGO (NZ) | 2018-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200109115-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | HMOX1, MB, NOS2 | AKT1 3529/4885IDO1 112/4885DRD2 2305/4885 |
| US-20180346420-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | HMOX1, MB, NOS2 | AKT1 3529/4885IDO1 112/4885DRD2 2305/4885 |
| US-11072584-B2 | Carbon monoxide releasing norbornenone compounds | HMOX1, MB, NOS2 | AKT1 3529/4885IDO1 112/4885DRD2 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.