Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984098 | 1.00 | HCAR2 (0.67) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9984524 | 1.00 | HCAR2 (0.67) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11258405 | 0.98 | HCAR2 (0.66) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30356595 | 0.93 | HCAR2 (0.65) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL543771 | 0.93 | ATM (0.55) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL544702 | 0.93 | ATM (0.55) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL543769 | 0.93 | ATM (0.55) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11251326 | 0.91 | ATM (0.57) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17695739 | 0.86 | ALDH1A1 (0.50) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17695740 | 0.86 | ALDH1A1 (0.50) | HCAR2ATMALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223958-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 2011-12-28 | — | — | EP | disclosed |