Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470751 | 0.86 | NR3C2 (0.38) | NR3C2MTNR1AMTNR1BKDM4EUSP2 | |
| SCHEMBL2401899 | 0.84 | CA12 (0.47) | NR3C2MTNR1AMTNR1BKDM4EUSP2 | |
| SCHEMBL13338130 | 0.78 | EGFR (0.48) | NR3C2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL5672847 | 0.76 | MCHR1 (0.45) | NR3C2ALDH1A1TSHRCA2CA9 | |
| SCHEMBL14421026 | 0.76 | TSHR (0.36) | NR3C2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL5746057 | 0.75 | SMN1; SMN2 (0.55) | ALDH1A1LMNATSHRSIGMAR1 | |
| SCHEMBL25335390 | 0.74 | MEN1 (0.46) | MTNR1AMTNR1BALDH1A1LMNAPPARG | |
| SCHEMBL8290870 | 0.74 | KCNN4 (0.38) | NR3C2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL4499222 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1LMNATSHRCA2 | |
| SCHEMBL28643624 | 0.73 | F2 (0.52) | ALDH1A1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9205156-B2 | Molecular imaging agents | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2015-12-08 | — | — | US | disclosed |
| US-20110293519-A1 | MOLECULAR IMAGING AGENTS | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110293519-A1 | MOLECULAR IMAGING AGENTS | TNNI3, FABP3, TNNT2 | NR3C2 4485/4885MTNR1A 1911/4885MTNR1B 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.