Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984770 | 0.86 | NR3C2 (0.44) | NR3C2ALDH1A1NR3C1MTNR1AMTNR1B | |
| SCHEMBL2401899 | 0.74 | CA12 (0.47) | NR3C2ALDH1A1MEN1KMT2ANR3C1 | |
| SCHEMBL31367786 | 0.73 | ALDH1A1 (0.32) | NR3C2ALDH1A1MEN1TP53KMT2A | |
| SCHEMBL10693144 | 0.71 | DHFR (0.44) | ALDH1A1MEN1TP53KMT2AESR1 | |
| SCHEMBL3693511 | 0.71 | TRPM8 (0.50) | NR3C2ALDH1A1KMT2ATRPM8TEAD1 | |
| SCHEMBL20670268 | 0.70 | MAPT (0.42) | NR3C2ALDH1A1TP53TRPM8LMNA | |
| SCHEMBL13338130 | 0.70 | EGFR (0.48) | NR3C2ALDH1A1MEN1TP53KMT2A | |
| SCHEMBL5672847 | 0.68 | MCHR1 (0.45) | NR3C2ALDH1A1TSHRCA2CA9 | |
| SCHEMBL2485496 | 0.68 | TRPM8 (0.44) | ALDH1A1MEN1TP53KMT2ATRPM8 | |
| SCHEMBL14421026 | 0.68 | TSHR (0.36) | NR3C2ALDH1A1MEN1KMT2ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11228569-A | — | — | None | — | — | JP | disclosed |
| JP-H11228569-A | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME | JAPAN TOBACCO INC | 1999-08-24 | — | — | JP | disclosed |