Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 5/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16158586 | 1.00 | THRB (0.36) | THRBLMNAGBA1OGAL3MBTL1 | |
| SCHEMBL18683146 | 1.00 | THRB (0.36) | THRBLMNAGBA1OGAL3MBTL1 | |
| SCHEMBL24038360 | 1.00 | THRB (0.36) | THRBLMNAGBA1OGAL3MBTL1 | |
| SCHEMBL25592953 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL13657213 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL13362009 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL23028656 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL16601877 | 0.95 | THRB (0.36) | THRBLMNAGBA1L3MBTL1 | |
| SCHEMBL12311769 | 0.83 | THRB (0.38) | THRBLMNA | |
| SCHEMBL24988552 | 0.83 | THRB (0.38) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159067-A2 | THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2011-12-22 | — | — | WO | claimed |