Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | WEE1 | P30291 | 6/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.42 |
| ▸ | AURKA | O14965 | 3/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.42 |
| ▸ | PAK4 | O96013 | 3/20 | 0.42 |
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.42 |
| ▸ | CSF1R | P07333 | 3/20 | 0.42 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | IGF1R | P08069 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786629 | 0.93 | HSF1 (0.48) | HSF1SRCHTR2AHTR2CTRPV1 | |
| SCHEMBL6793338 | 0.89 | HSF1 (0.64) | HSF1TRPV1WEE1ALKROCK1 | |
| SCHEMBL6789036 | 0.86 | HSF1 (0.62) | HSF1ROCK1ROCK2 | |
| SCHEMBL6787562 | 0.85 | HSF1 (0.59) | HSF1TRPV1ROCK1EGFRROCK2 | |
| SCHEMBL9984487 | 0.83 | HSF1 (0.59) | HSF1ROCK1ROCK2CCR2 | |
| SCHEMBL6788873 | 0.81 | HSF1 (0.53) | HSF1TRPV1WEE1ALKROCK1 | |
| SCHEMBL9985473 | 0.80 | HSF1 (0.62) | HSF1WEE1ALKROCK1AURKA | |
| SCHEMBL9985436 | 0.80 | HSF1 (0.62) | HSF1ROCK1ROCK2CCR2 | |
| SCHEMBL6787557 | 0.78 | HSF1 (0.52) | HSF1TRPV1ROCK1PDGFRAPDGFRB | |
| SCHEMBL6786712 | 0.78 | HSF1 (0.49) | HSF1TRPV1FGFR1PDGFRAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110306641-A1 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL PREPARATION INCLUDING SAME | DONG WHA PHARM. CO., LTD. (KR) | 2011-12-15 | — | — | US | claimed |
| US-20110306641-A1 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL PREPARATION INCLUDING SAME | DONG WHA PHARM. CO., LTD. (KR) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306641-A1 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL PREPARATION INCLUDING SAME | PTMS, NOS3, NOS1 | HSF1 4573/4885SRC 1882/4885HTR2A 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.