SCHEMBL9985258

SCHEMBL9985258

C=Cc1cccc(Cl)c1Cl.C=Cc1ccccc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
TSHR P16473 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
PPP1R15A O75807 1/20 0.38
MELK Q14680 1/20 0.38
PPP1R15B Q5SWA1 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 4/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
GSR P00390 1/20 0.35
PTGS2 P35354 1/20 0.34
P2RX7 Q99572 3/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7049963 0.86 ALDH1A1 (0.75) ALDH1A1TSHRSMN1; SMN2LMNAGSR
SCHEMBL30587141 0.86 ALDH1A1 (0.65) ALDH1A1TSHRSMN1; SMN2PPP1R15AMELK
SCHEMBL40188 0.86 ALDH1A1 (0.65) ALDH1A1TSHRSMN1; SMN2PPP1R15AMELK
SCHEMBL5491734 0.84 ALDH1A1 (0.78) ALDH1A1TSHRSMN1; SMN2PPP1R15AMELK
SCHEMBL3686691 0.82 ALDH1A1 (0.48) ALDH1A1TSHRL3MBTL1LMNAKMT2A
SCHEMBL29391686 0.82
SCHEMBL14887 0.82
SCHEMBL678151 0.82 ALDH1A1 (0.56) ALDH1A1TSHRKMT2AMEN1RAB9A
Ethyl Chloride SCHEMBL28140509 0.80 ALDH1A1 (0.64) ALDH1A1TSHRSMN1; SMN2LMNAKMT2A
SCHEMBL10436179 0.80 ALDH1A1 (0.50) ALDH1A1TSHRSMN1; SMN2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392611-A2 Functionalized ethylene/alpha-olefin interpolymer compositions Dow Global Technologies LLC (US) 2011-12-07 EP claimed