Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23119744 | 0.82 | GAA (0.41) | GAA | |
| SCHEMBL20758911 | 0.80 | GAA (0.40) | GAA | |
| SCHEMBL6560160 | 0.80 | OR51E2 (0.39) | GAA | |
| SCHEMBL16190024 | 0.80 | — | — | |
| SCHEMBL9986841 | 0.78 | OR51E2 (0.34) | GAA | |
| SCHEMBL23119745 | 0.78 | GAA (0.48) | GAA | |
| SCHEMBL20633689 | 0.78 | OR51E2 (0.37) | GAA | |
| SCHEMBL16503412 | 0.73 | — | — | |
| SCHEMBL503340 | 0.72 | ALDH1A1 (0.33) | GAA | |
| SCHEMBL1133336 | 0.72 | NEK2 (0.39) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585444-A1 | AZASPIROHEXANONES AS INHIBITORS OF 11-BETA-HSD1 FOR THE TREATMENT OF METABOLIC DISORDERS | Boehringer Ingelheim International GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011161128-A1 | AZASPIROHEXANONES AS INHIBITORS OF 11-BETA-HSD1 FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |