Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987026 | 1.00 | DPP4 (0.41) | DPP4DPP7DPP8NPC1RAB9A | |
| SCHEMBL9987006 | 0.82 | DPP4 (0.43) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL898718 | 0.81 | DPP4 (0.45) | DPP4DPP7DPP8NPC1RAB9A | |
| SCHEMBL9986469 | 0.81 | DPP4 (0.45) | DPP4DPP7DPP8NPC1RAB9A | |
| SCHEMBL9987320 | 0.78 | DPP4 (0.39) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL9986836 | 0.77 | DPP4 (0.41) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL14550109 | 0.72 | DPP4 (0.43) | DPP4DPP7DPP8DPP9CYP3A4 | |
| Tert-Butylamine SCHEMBL898670 | 0.71 | DPP4 (0.43) | DPP4DPP7DPP8NPC1RAB9A | |
| SCHEMBL897883 | 0.71 | DPP4 (0.44) | DPP4DPP7DPP8NPC1RAB9A | |
| SCHEMBL743824 | 0.71 | DPP4 (0.44) | DPP4DPP7DPP8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397141-A1 | Process for the synthesis of beta-amino acids and derivatives thereof | LEK Pharmaceuticals d.d. (SI) | 2011-12-21 | — | — | EP | disclosed |