Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986836 | 0.84 | DPP4 (0.41) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL9987320 | 0.83 | DPP4 (0.39) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL9987026 | 0.82 | DPP4 (0.41) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL9986355 | 0.82 | DPP4 (0.41) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL9985996 | 0.79 | DPP4 (0.48) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL9985994 | 0.79 | DPP4 (0.48) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL3727485 | 0.69 | DPP4 (0.46) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL3727486 | 0.69 | DPP4 (0.46) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL743042 | 0.67 | DPP4 (0.53) | DPP4DPP7DPP8CYP3A4 | |
| SCHEMBL571909 | 0.67 | DPP4 (0.53) | DPP4DPP7DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397141-A1 | Process for the synthesis of beta-amino acids and derivatives thereof | LEK Pharmaceuticals d.d. (SI) | 2011-12-21 | — | — | EP | disclosed |