Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pirodavir SCHEMBL146440 | 0.87 | HRH3 (0.46) | GPR119NR1I2MAPTKDM4EALDH1A1 | |
| SCHEMBL7486949 | 0.86 | GPR119 (0.40) | GPR119NR1I2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5884689 | 0.85 | KCNH2 (0.39) | GPR119NR1I2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13021438 | 0.85 | PPARG (0.39) | GPR119NR1I2MAPTKDM4EALDH1A1 | |
| SCHEMBL5884333 | 0.85 | KCNH2 (0.39) | GPR119NR1I2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1419892 | 0.85 | GPR119 (0.43) | GPR119NR1I2TP53MEN1KMT2A | |
| SCHEMBL5883991 | 0.84 | GPR119 (0.38) | GPR119NR1I2MAPTKDM4EALDH1A1 | |
| SCHEMBL1666187 | 0.82 | CYP1A2 (0.39) | GPR119RAB9A | |
| SCHEMBL10327457 | 0.82 | ENPP1 (0.41) | GPR119KDM4EALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL1664257 | 0.82 | PPARG (0.37) | GPR119NR1I2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585067-A1 | COMPOUND FOR THE TREATMENT OF ENTEROVIRUSES | Biota Scientific Management Pty Ltd (AU) | 2013-05-01 | — | — | EP | disclosed |
| CN-102844032-A | Compounds for the treatment of respiratory conditions or diseases | BIOTA SCIENT MAN | 2012-12-26 | — | — | CN | disclosed |
| WO-2011160191-A1 | COMPOUND FOR THE TREATMENT OF ENTEROVIRUSES | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-29 | — | — | WO | disclosed |