Pirodavir

Pirodavir

SCHEMBL146440

CCOC(=O)c1ccc(OCCC2CCN(c3ccc(C)nn3)CC2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.46
KCNH2 Q12809 1/20 0.46
MAPT P10636 3/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
GPR119 Q8TDV5 2/20 0.44
TBXAS1 P24557 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PIK3CA P42336 1/20 0.43
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NR1I2 O75469 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9209675 0.91 HRH3 (0.44) HRH3KCNH2MAPTKDM4ELMNA
SCHEMBL9209752 0.91 HRH3 (0.44) HRH3KCNH2MAPTKDM4ELMNA
SCHEMBL9218863 0.91 HRH3 (0.44) HRH3KCNH2MAPTKDM4ELMNA
SCHEMBL14191673 0.89 NR1I2 (0.48) HRH3KCNH2MAPTKDM4ELMNA
SCHEMBL1419892 0.88 GPR119 (0.43) GPR119KMT2ANR1I2MAPK1
SCHEMBL9218579 0.88 HRH3 (0.43) HRH3KCNH2MAPTKDM4ELMNA
SCHEMBL9218008 0.87 KDM4E (0.44) HRH3KCNH2MAPTKDM4EGPR119
SCHEMBL9986408 0.87 GPR119 (0.45) MAPTKDM4EGPR119KMT2ANPC1
SCHEMBL9218658 0.86 HRH3 (0.45) HRH3KCNH2MAPTKDM4ELMNA
SCHEMBL9220790 0.86 MEN1 (0.47) HRH3KCNH2MAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1708 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705284-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO Emory University (US) 2026-03-11 EP claimed
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO claimed
WO-2025235664-A1 PURINE NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2025-11-13 WO claimed
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO EMORY UNIVERSITY 2025-09-11 US claimed
WO-2024233354-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2024-11-14 WO claimed
EP-4452220-A1 NOVEL ANTIVIRAL COMPOSITIONS COMPRISING OLEIC ACID Subintro Limited (GB) 2024-10-30 EP claimed
WO-2024215771-A1 SUBSTITUTED PHENYL ETHYNYL PYRIMIDINES AS POTENT INHIBITORS OF ALPHAVIRUSES SOUTHERN RESEARCH INSTITUTE (US) 2024-10-17 WO claimed
CN-118488831-A Novel antiviral compositions comprising oleic acid 苏宾特罗有限公司 2024-08-13 CN claimed
CN-117881402-A Nucleotide and nucleoside therapeutic compositions, combinations, and uses related thereto 埃默里大学 2024-04-12 CN claimed
CN-115919823-B Application of benserazide hydrochloride in preparing medicament for treating diseases caused by respiratory syncytial virus 浙江艾特为生物科技有限公司 2024-04-05 CN claimed
US-20040092583-A1 Treatment for inhibiting neoplastic lesions SHANAHAN-PRENDERGAST ELIZABETH (IE) 2004-05-13 US claimed
US-20040077601-A1 Methods and compositions relating to isoleucine boroproline compounds POINT THERAPEUTICS, INC. 2004-04-22 US claimed
WO-2004004658-A2 METHODS AND COMPOSITIONS RELATING TO ISOLEUCINE BOROPROLINE COMPOUNDS POINT THERAPEUTICS, INC. (US) 2004-01-15 WO claimed
US-6576636-B2 Treating a noncentral nervous system by administering a covalent conjugate of a C8-26, unbranched, naturally occurring fatty acid and a drug, provided the drug is not an adenosine receptor agonist/antagonist; anticarcinogenics PROTARGA, INC. 2003-06-10 US claimed
WO-2003030934-A2 CPG FORMULATIONS AND RELATED METHODS MERIAL LIMITED (US) 2003-04-17 WO claimed
EP-1214317-A1 ANTIVIRAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 2002-06-19 EP claimed
WO-2001097749-A2 THE USE OF SYNTHETIC, NON-HORMONAL 21-AMINOSTEROIDS AND THEREOF KOTZE, GAVIN, SALOMON (ZA) 2001-12-27 WO claimed
WO-2001019822-A1 ANTIVIRAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2001-03-22 WO claimed
WO-1998017282-A1 METHODS OF USING SUCROSE OCTASULFATE TO TREAT OR PREVENT ENVELOPED VIRUS INFECTION VERTEX PHARMACEUTICALS INCORPORATED (US) 1998-04-30 WO claimed
US-4992433-A Viricides JANSSEN PHARMACEUTICA N.V. (BE) 1991-02-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO NTPCR, TYMP, MTAP HRH3 4380/4885KCNH2 4762/4885MAPT 3165/4885
US-20040092583-A1 Treatment for inhibiting neoplastic lesions VHL, IDH2, AIFM2 HRH3 347/4885KCNH2 3181/4885MAPT 4347/4885
US-20040077601-A1 Methods and compositions relating to isoleucine boroproline compounds BCAT1, BCAT2, APOB HRH3 2290/4885KCNH2 1015/4885MAPT 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.