SCHEMBL998683

SCHEMBL998683

CCCN(CCC)Cc1[c]cccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.42
ALDH1A1 P00352 1/20 0.39
HTR1A P08908 2/20 0.37
DRD3 P35462 2/20 0.36
BCHE P06276 5/20 0.36
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.34
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
DRD2 P14416 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
TP53 P04637 1/20 0.32
RORC P51449 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996139 0.84 HRH3 (0.39) HRH3ALDH1A1HTR1ADRD3TSHR
SCHEMBL8125074 0.82 KCNH2 (0.42) HTR1ADRD3TSHROPRM1MEN1
SCHEMBL4044770 0.80 KMT2A (0.41) ALDH1A1POLBMEN1KMT2A
SCHEMBL4310389 0.79 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10
SCHEMBL160311 0.77 ALDH1A1 (0.46) HRH3ALDH1A1TSHRHSD17B10MEN1
SCHEMBL28558829 0.75 ALDH1A1 (0.44) HRH3ALDH1A1TSHRHSD17B10MEN1
SCHEMBL28636919 0.75 ALDH1A1 (0.44) HRH3ALDH1A1TSHRHSD17B10MEN1
SCHEMBL27755603 0.75 ALDH1A1 (0.44) HRH3ALDH1A1TSHRHSD17B10MEN1
SCHEMBL6555817 0.74 CNR2 (0.43) ALDH1A1TSHROPRM1OPRD1OPRK1
SCHEMBL4658283 0.74 CHRNB2 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456435-A1 HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE The Board of Trustees of The Leland Stanford Junior University (US) 2012-05-30 EP claimed
WO-2011011514-A1 HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-01-27 WO claimed
EP-2627324-A2 SUBSTITUTED BENZAMIDES AND THEIR USES The Board of Trustees of The Leland Stanford Junior University (US) 2013-08-21 EP disclosed
EP-2456435-A1 HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE The Board of Trustees of The Leland Stanford Junior University (US) 2012-05-30 EP disclosed
WO-2012051117-A2 SUBSTITUTED BENZAMIDES AND THEIR USES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2012-04-19 WO disclosed
WO-2011011514-A1 HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-01-27 WO disclosed