Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448531 | 0.81 | DDAH1 (0.42) | DDAH1CYP1A2CYP2C9POLBPKM | |
| SCHEMBL293984 | 0.80 | NR3C1 (0.47) | MAPTPKMLMNAGAAHTT | |
| SCHEMBL292904 | 0.77 | DDAH1 (0.42) | DDAH1CYP1A2CYP2C9POLBPKM | |
| SCHEMBL292461 | 0.72 | NR3C1 (0.48) | CYP3A4 | |
| SCHEMBL4562346 | 0.71 | DDAH1 (0.59) | DDAH1CYP1A2MAPTCYP2C9POLB | |
| SCHEMBL10761755 | 0.68 | DDAH1 (0.61) | DDAH1CYP1A2MAPTCYP2C9POLB | |
| SCHEMBL14340588 | 0.67 | NR3C1 (0.61) | CYP3A4 | |
| SCHEMBL1633594 | 0.65 | NR3C1 (0.69) | — | |
| SCHEMBL2277460 | 0.65 | DDAH1 (0.59) | DDAH1CYP1A2CYP2C9POLBPKM | |
| SCHEMBL30679038 | 0.65 | DDAH1 (0.59) | DDAH1CYP1A2CYP2C9POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |