Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.64 |
| ▸ | PGR | P06401 | 5/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292687 | 0.95 | NR3C1 (0.77) | NR3C1CYP3A4NR3C2PGRKCNH2 | |
| SCHEMBL291539 | 0.93 | NR3C1 (0.68) | NR3C1CYP3A4NR3C2PGRKCNH2 | |
| SCHEMBL3807894 | 0.88 | NR3C1 (0.64) | NR3C1CYP3A4NR3C2PGRKCNH2 | |
| SCHEMBL4571045 | 0.84 | NR3C1 (0.54) | NR3C1CYP3A4NR3C2PGRKCNH2 | |
| SCHEMBL6384914 | 0.83 | NR3C1 (0.56) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL6385232 | 0.83 | NR3C1 (0.71) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL6385448 | 0.83 | NR3C1 (1.00) | NR3C1CYP3A4NR3C2PGRKCNH2 | |
| SCHEMBL15756249 | 0.80 | NR3C1 (0.80) | NR3C1CYP3A4NR3C2PGRKCNH2 | |
| SCHEMBL15756252 | 0.80 | NR3C1 (0.56) | NR3C1CYP3A4NR3C2PGRKCNH2 | |
| SCHEMBL3807896 | 0.79 | NR3C1 (0.52) | NR3C1CYP3A4NR3C2PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |