Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.75 |
| ▸ | PGR | P06401 | 7/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290889 | 0.90 | NR3C1 (0.69) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL291217 | 0.90 | NR3C1 (0.69) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL6385448 | 0.87 | NR3C1 (1.00) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL291982 | 0.85 | NR3C1 (0.85) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL15756274 | 0.85 | NR3C1 (0.84) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL5800544 | 0.85 | NR3C1 (0.86) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL9987961 | 0.84 | NR3C1 (0.65) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL1931034 | 0.80 | NR3C1 (0.54) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL1931073 | 0.80 | NR3C1 (0.54) | NR3C1CYP3A4PGRNR3C2KCNH2 | |
| SCHEMBL1680239 | 0.80 | NR3C1 (0.69) | NR3C1CYP3A4PGRNR3C2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |