Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985981 | 0.91 | PIM1 (0.36) | PIM1PIM2ALDH3A1TSHRLMNA | |
| SCHEMBL2986526 | 0.86 | PIM1 (0.35) | PIM1PIM2ALDH3A1TSHRLMNA | |
| SCHEMBL2991201 | 0.86 | PIM1 (0.35) | PIM1PIM2ALDH3A1TSHRLMNA | |
| SCHEMBL2991179 | 0.82 | NPC1 (0.36) | PIM1PIM2ALDH1A1 | |
| SCHEMBL2988252 | 0.81 | LMNA (0.34) | PIM1PIM2ALDH3A1TSHRLMNA | |
| SCHEMBL2990014 | 0.80 | PTGDR2 (0.42) | ALDH3A1TSHRPTGDR2CYP3A4ALDH1A1 | |
| SCHEMBL2991843 | 0.78 | PIM1 (0.36) | PIM1PIM2ALDH3A1TSHRLMNA | |
| SCHEMBL13103442 | 0.78 | L3MBTL1 (0.37) | PIM1PIM2ALDH3A1TSHRLMNA | |
| SCHEMBL13093819 | 0.76 | L3MBTL1 (0.42) | ALDH3A1TSHRLMNAPTGDR2ALDH1A1 | |
| SCHEMBL1749068 | 0.75 | TP53 (0.41) | PIM1PIM2ALDH3A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799691-B1 | NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2011-12-21 | — | — | EP | disclosed |