Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 15/20 | 0.46 |
| ▸ | PGR | P06401 | 14/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291599 | 0.79 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL3533407 | 0.77 | NR3C1 (0.43) | NR3C1NR3C2PGRDRD2DRD3 | |
| SCHEMBL4476759 | 0.73 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL292847 | 0.71 | NR3C1 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL292133 | 0.71 | NR3C1 (0.44) | NR3C1NR3C2PGR | |
| SCHEMBL3531222 | 0.71 | NR3C1 (0.38) | NR3C1NR3C2PGRDRD2DRD3 | |
| SCHEMBL290989 | 0.70 | NR3C1 (0.47) | NR3C1NR3C2PGR | |
| SCHEMBL291852 | 0.69 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL4816869 | 0.67 | PTGS2 (0.42) | NR3C1NR3C2PGRDRD2DRD3 | |
| SCHEMBL448789 | 0.67 | NR3C1 (0.77) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |