Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.55 |
| ▸ | RXRA | P19793 | 7/20 | 0.48 |
| ▸ | RXRB | P28702 | 7/20 | 0.48 |
| ▸ | RXRG | P48443 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988511 | 0.94 | MALT1 (0.52) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988395 | 0.93 | MALT1 (0.55) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9989537 | 0.93 | MALT1 (0.59) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988938 | 0.92 | MALT1 (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988822 | 0.92 | MALT1 (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988478 | 0.91 | MALT1 (0.56) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988678 | 0.91 | RXRA (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988463 | 0.90 | RXRA (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988479 | 0.90 | MALT1 (0.49) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9989257 | 0.89 | MALT1 (0.51) | MALT1RXRARXRBRXRGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |