Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.59 |
| ▸ | RXRA | P19793 | 5/20 | 0.52 |
| ▸ | RXRB | P28702 | 5/20 | 0.52 |
| ▸ | RXRG | P48443 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989721 | 0.93 | MALT1 (0.56) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988478 | 0.93 | MALT1 (0.56) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988401 | 0.93 | MALT1 (0.55) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988395 | 0.93 | MALT1 (0.55) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988512 | 0.93 | MALT1 (0.57) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988938 | 0.92 | MALT1 (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988822 | 0.92 | MALT1 (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988678 | 0.91 | RXRA (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988463 | 0.90 | RXRA (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988840 | 0.89 | MALT1 (0.52) | MALT1RXRARXRBRXRGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |