Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989017 | 0.92 | MALT1 (0.53) | MALT1RXRARXRBRXRGCACNA1G | |
| SCHEMBL9988443 | 0.88 | NAMPT (0.44) | MALT1RXRARXRBRXRGNAMPT | |
| SCHEMBL9988478 | 0.88 | MALT1 (0.56) | MALT1RXRARXRBRXRGMMP13 | |
| SCHEMBL9988866 | 0.88 | MALT1 (0.49) | MALT1RXRARXRBRXRGMMP13 | |
| SCHEMBL9988512 | 0.87 | MALT1 (0.57) | MALT1RXRARXRBRXRGCACNA1G | |
| SCHEMBL9988522 | 0.87 | MALT1 (0.50) | MALT1RXRARXRBRXRGDGAT2 | |
| SCHEMBL9990171 | 0.86 | MALT1 (0.50) | MALT1RXRARXRBRXRGPTGER4 | |
| SCHEMBL9989263 | 0.85 | MALT1 (0.55) | MALT1RXRARXRBRXRGCACNA1G | |
| SCHEMBL9988484 | 0.84 | MALT1 (0.47) | MALT1RXRARXRBRXRGILK | |
| SCHEMBL9989721 | 0.84 | MALT1 (0.56) | MALT1RXRARXRBRXRGCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |