Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989144 | 0.89 | SMN1; SMN2 (0.49) | MALT1HPGDALOX15TDP1NTRK1 | |
| SCHEMBL9989046 | 0.88 | TP53 (0.50) | MALT1HPGDALOX15TDP1NTRK1 | |
| SCHEMBL9989017 | 0.88 | MALT1 (0.53) | MALT1RXRARXRBRXRGPOLB | |
| SCHEMBL9988484 | 0.87 | MALT1 (0.47) | MALT1HPGDKMT2ARXRARXRB | |
| SCHEMBL9988495 | 0.87 | MALT1 (0.49) | MALT1RXRARXRBRXRGDGAT2 | |
| SCHEMBL9989719 | 0.87 | HPGD (0.48) | MALT1HPGDALOX15TDP1NTRK1 | |
| SCHEMBL9990171 | 0.84 | MALT1 (0.50) | MALT1RXRARXRBRXRG | |
| SCHEMBL9988866 | 0.84 | MALT1 (0.49) | MALT1HPGDKMT2ARXRARXRB | |
| SCHEMBL9988478 | 0.84 | MALT1 (0.56) | MALT1RXRARXRBRXRG | |
| SCHEMBL9988512 | 0.82 | MALT1 (0.57) | MALT1RXRARXRBRXRGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |