Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 4/20 | 0.42 |
| ▸ | RXRB | P28702 | 4/20 | 0.42 |
| ▸ | RXRG | P48443 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988522 | 0.87 | MALT1 (0.50) | MALT1RXRARXRBRXRGHPGD | |
| SCHEMBL9989017 | 0.87 | MALT1 (0.53) | MALT1RXRARXRBRXRGMMP13 | |
| SCHEMBL9988866 | 0.86 | MALT1 (0.49) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9988495 | 0.84 | MALT1 (0.49) | MALT1RXRARXRBRXRGILK | |
| SCHEMBL9988915 | 0.84 | CA1 (0.47) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9988478 | 0.83 | MALT1 (0.56) | MALT1RXRARXRBRXRGTHRB | |
| SCHEMBL9990171 | 0.82 | MALT1 (0.50) | MALT1RXRARXRBRXRGMMP13 | |
| SCHEMBL9989263 | 0.81 | MALT1 (0.55) | MALT1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9988512 | 0.80 | MALT1 (0.57) | MALT1RXRARXRBRXRGTHRB | |
| SCHEMBL9989144 | 0.80 | SMN1; SMN2 (0.49) | MALT1ALDH1A1HPGDTHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |