Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675694 | 0.85 | ALDH1A1 (0.44) | GRIA4ACE2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14966615 | 0.84 | GRIA4 (0.49) | GRIA4TP53TSHRANPEPRXRA | |
| SCHEMBL14549283 | 0.83 | TSHR (0.56) | GRIA4TP53TSHRANPEPRXRA | |
| SCHEMBL10031628 | 0.83 | TSHR (0.56) | GRIA4TP53TSHRANPEPRXRA | |
| SCHEMBL115710 | 0.83 | TSHR (0.56) | GRIA4TP53TSHRANPEPRXRA | |
| SCHEMBL548540 | 0.83 | KMT2A (0.48) | MAPTKMT2AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL11147966 | 0.82 | ALDH1A1 (0.52) | MAPTKMT2AALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL2641075 | 0.82 | ABCB11 (0.52) | TSHRTRPA1 | |
| SCHEMBL9362701 | 0.82 | GRIA4 (0.50) | GRIA4TP53TSHRANPEPRXRA | |
| SCHEMBL17363472 | 0.82 | TAAR1 (0.57) | GRIA4TP53TSHRANPEPRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516369-B1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LTD (IN) | 2015-07-22 | — | — | EP | claimed |
| US-20130072573-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2013-03-21 | — | — | US | claimed |
| EP-2516369-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | Harman Finochem Limited (IN) | 2012-10-31 | — | — | EP | claimed |
| WO-2011161687-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |
| CN-103930409-B | Armaticity amide thiazole, containing its cosmetic or dermatological preparations and their purposes overcoming and preventing less desirable cutaneous pigmentation | 拜尔斯道夫股份公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-2595989-B1 | HETEROCYCLIC CHROMENE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | VERTEX PHARMA (US) | 2016-07-13 | — | — | EP | disclosed |
| US-20150239866-A1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK CANADA INC. (CA) | 2015-08-27 | — | — | US | disclosed |
| EP-2516369-B1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LTD (IN) | 2015-07-22 | — | — | EP | disclosed |
| EP-2780014-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013075083-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2013-05-23 | — | — | WO | disclosed |
| US-20130072573-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2013-03-21 | — | — | US | disclosed |
| US-20130072573-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2013-03-21 | — | — | US | disclosed |
| EP-2516369-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | Harman Finochem Limited (IN) | 2012-10-31 | — | — | EP | disclosed |
| EP-2516369-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | Harman Finochem Limited (IN) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011161687-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011161687-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | HARMAN FINOCHEM LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |
| US-4219570-A | Insect repellents and a method of repelling insects | AJINOMOTO COMPANY, INCORPORATED (JP) | 1980-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239866-A1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | SYK, BTK, TYRO3 | GRIA4 3135/4885TP53 625/4885TSHR 1340/4885 |
| US-20130072573-A1 | PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL | CYP2B6, CYP2D6, CYP2A6 | GRIA4 1429/4885TP53 2438/4885TSHR 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.