Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | CCKAR | P32238 | 7/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988493 | 0.91 | MALT1 (0.56) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9989011 | 0.90 | RXRA (0.48) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9990308 | 0.88 | RXRA (0.47) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9989590 | 0.85 | RXRA (0.44) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9990141 | 0.84 | RXRA (0.51) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9989355 | 0.84 | MALT1 (0.62) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9988853 | 0.83 | MAPT (0.48) | MALT1TP53MAPT | |
| SCHEMBL9989283 | 0.83 | TP53 (0.45) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9988942 | 0.83 | TP53 (0.44) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9989578 | 0.83 | RXRA (0.47) | RXRARXRBRXRGCCKARMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |