Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 4/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990181 | 0.92 | MALT1 (0.53) | RXRARXRBRXRGLMNAMALT1 | |
| SCHEMBL9989653 | 0.91 | RXRA (0.53) | RXRARXRBRXRGLMNACCKAR | |
| SCHEMBL9993178 | 0.91 | RXRA (0.47) | RXRARXRBRXRGLMNAMALT1 | |
| SCHEMBL9988493 | 0.91 | MALT1 (0.56) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9989490 | 0.90 | RXRA (0.50) | RXRARXRBRXRGLMNAMALT1 | |
| SCHEMBL9989011 | 0.88 | RXRA (0.48) | RXRARXRBRXRGLMNACCKAR | |
| SCHEMBL9988682 | 0.88 | RXRA (0.48) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9989355 | 0.83 | MALT1 (0.62) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9989590 | 0.83 | RXRA (0.44) | RXRARXRBRXRGCCKARMALT1 | |
| SCHEMBL9989283 | 0.83 | TP53 (0.45) | RXRARXRBRXRGCCKARMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |