Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928304 | 0.78 | — | — | |
| SCHEMBL771276 | 0.77 | KMT2A (0.35) | — | |
| SCHEMBL5586144 | 0.75 | FKBP1A (0.44) | FKBP1A | |
| SCHEMBL12765348 | 0.75 | — | — | |
| SCHEMBL1069094 | 0.75 | KMT2A (0.33) | — | |
| SCHEMBL9988709 | 0.74 | CA1 (0.50) | — | |
| SCHEMBL1376664 | 0.74 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL5181697 | 0.73 | CA1 (0.48) | FKBP1A | |
| SCHEMBL1065699 | 0.72 | KMT2A (0.52) | — | |
| SCHEMBL1067872 | 0.72 | EPHX2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397462-A2 | Compounds, compositions and methods of treatment for heart failure | Cytokinetics, Inc. (US) | 2011-12-21 | — | — | EP | disclosed |