Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207776 | 0.85 | — | — | |
| SCHEMBL1065699 | 0.79 | KMT2A (0.52) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL771276 | 0.79 | KMT2A (0.35) | CA1CA2POLBUSP2TSHR | |
| SCHEMBL1069094 | 0.77 | KMT2A (0.33) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL9987867 | 0.76 | EPHX2 (0.34) | CA1CA2POLBKMT2A | |
| SCHEMBL1067872 | 0.74 | EPHX2 (0.34) | KMT2A | |
| SCHEMBL9988905 | 0.74 | FKBP1A (0.33) | — | |
| SCHEMBL1068447 | 0.74 | GAA (0.57) | KMT2A | |
| SCHEMBL1067874 | 0.71 | L3MBTL1 (0.41) | USP2TSHRKMT2ACYP3A4CYP2C9 | |
| SCHEMBL4790629 | 0.70 | ALDH1A1 (0.57) | POLBUSP2TSHRKMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397462-A2 | Compounds, compositions and methods of treatment for heart failure | Cytokinetics, Inc. (US) | 2011-12-21 | — | — | EP | disclosed |