SCHEMBL9989358

SCHEMBL9989358

C=Cc1ccc(CN(C(O)CC)C(O)CC)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
HDAC6 Q9UBN7 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
HDAC1 Q13547 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
HDAC3 O15379 1/20 0.32
PYCR1 P32322 1/20 0.32
TSHR P16473 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9988958 0.81 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1HDAC6HDAC8
SCHEMBL6808117 0.79 HDAC8 (0.46) ALDH1A1TAS1R3TAS1R1HDAC6HDAC8
SCHEMBL5141244 0.78 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1HDAC6HDAC8
SCHEMBL465333 0.77 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL20468050 0.76 POLB (0.38) ALDH1A1TAS1R3TAS1R1HDAC6HDAC8
SCHEMBL20468080 0.75 ALDH1A1 (0.35) ALDH1A1TAS1R3TAS1R1HDAC6HDAC8
SCHEMBL94062 0.73 HRH3 (0.59) ALDH1A1HDAC6HDAC8PYCR1HRH3
SCHEMBL17527583 0.73 ALDH1A1 (0.46) ALDH1A1TAS1R3TAS1R1HDAC6HDAC8
SCHEMBL18874552 0.72 ALDH1A1 (0.50) ALDH1A1HDAC6HDAC8CHRNB2CHRNB4
SCHEMBL6391713 0.72 PYCR1 (0.50) ALDH1A1HDAC6HDAC8HDAC3PYCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1311572-B1 BIOCIDAL POLYURETHANE COMPOSITIONS AND METHOD OF USE 3M INNOVATIVE PROPERTIES CO (US) 2011-12-21 EP disclosed