Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.63 |
| ▸ | CTSS | P25774 | 2/20 | 0.63 |
| ▸ | CTSK | P43235 | 2/20 | 0.63 |
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989471 | 1.00 | CTSL (0.63) | CTSLCTSSCTSKTAS1R3TAS1R1 | |
| SCHEMBL701973 | 0.92 | TAS1R3 (0.68) | CTSLCTSSCTSKTAS1R3TAS1R1 | |
| SCHEMBL701974 | 0.92 | TAS1R3 (0.68) | CTSLCTSSCTSKTAS1R3TAS1R1 | |
| SCHEMBL20853665 | 0.81 | TAS1R3 (0.61) | CTSLCTSSCTSKTAS1R3TAS1R1 | |
| SCHEMBL12071089 | 0.81 | TAS1R3 (0.66) | TAS1R3TAS1R1KMT2AHDAC3HDAC4 | |
| SCHEMBL12072870 | 0.81 | TAS1R3 (0.66) | TAS1R3TAS1R1KMT2AHDAC3HDAC4 | |
| SCHEMBL12072230 | 0.80 | TAS1R3 (0.65) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL12071238 | 0.80 | TAS1R3 (0.65) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL12071087 | 0.78 | TAS1R3 (0.62) | TAS1R3TAS1R1 | |
| SCHEMBL12073443 | 0.78 | TAS1R3 (0.62) | TAS1R3TAS1R1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |