Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990181 | 0.95 | MALT1 (0.53) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9990308 | 0.90 | RXRA (0.47) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9993178 | 0.89 | RXRA (0.47) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9989653 | 0.89 | RXRA (0.53) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9989355 | 0.86 | MALT1 (0.62) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9988456 | 0.84 | SLC16A3 (0.53) | RXRARXRBRXRGALOX5PTGS2 | |
| Hydrochloric Acid SCHEMBL9466114 | 0.83 | RXRA (0.68) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9989050 | 0.83 | CCKAR (0.58) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9988359 | 0.82 | MALT1 (0.67) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9988534 | 0.82 | MALT1 (0.55) | RXRARXRBRXRGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |