Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997660 | 0.87 | MAPT (0.49) | MAPTTSHRCA12CA1CA2 | |
| SCHEMBL997314 | 0.83 | TSHR (0.51) | MAPTTSHRCA12CA1CA2 | |
| SCHEMBL998319 | 0.79 | TSHR (0.51) | MAPTTSHRCA12CA1CA2 | |
| SCHEMBL7361541 | 0.78 | CA1 (0.65) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL31582154 | 0.77 | ALDH1A1 (0.49) | MAPTTSHRCA12CA1CA2 | |
| SCHEMBL22129276 | 0.74 | TYR (0.51) | MAPTTSHRCA12CA1CA2 | |
| SCHEMBL858817 | 0.74 | AR (0.57) | ALDH1A1KDM4ESMN1; SMN2HSD17B10AR | |
| SCHEMBL10746832 | 0.74 | HAO1 (0.51) | MAPTTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL996657 | 0.73 | CA12 (0.41) | MAPTTSHRCA12CA1CA2 | |
| SCHEMBL16360980 | 0.73 | MEN1 (0.66) | MAPTTSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |