Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998950 | 0.87 | MAPT (0.39) | MAPTKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL998319 | 0.83 | TSHR (0.51) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL9645442 | 0.81 | ALDH1A1 (0.50) | MAPTKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL10651588 | 0.80 | PTPN1 (0.48) | MAPTKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL31582154 | 0.80 | ALDH1A1 (0.49) | MAPTKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL997314 | 0.79 | TSHR (0.51) | MAPTKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL9667921 | 0.78 | KDM4E (0.77) | MAPTKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL16360980 | 0.77 | MEN1 (0.66) | MAPTKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL996657 | 0.77 | CA12 (0.41) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL1545562 | 0.75 | PKM (0.52) | MAPTKMT2AALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |