Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988518 | 0.93 | MALT1 (0.52) | MALT1CACNA1GCACNA1HTSHRRECQL | |
| SCHEMBL9988467 | 0.92 | MALT1 (0.45) | MALT1TSHRRXRARXRBRXRG | |
| SCHEMBL9989257 | 0.92 | MALT1 (0.51) | MALT1RXRARXRBRXRGSRC | |
| SCHEMBL9989656 | 0.90 | MALT1 (0.53) | MALT1CACNA1GCACNA1HTSHRRXRA | |
| SCHEMBL9988512 | 0.90 | MALT1 (0.57) | MALT1CACNA1GCACNA1HRXRARXRB | |
| SCHEMBL9988373 | 0.88 | MALT1 (0.54) | MALT1CACNA1GCACNA1HRXRARXRB | |
| SCHEMBL9989263 | 0.88 | MALT1 (0.55) | MALT1CACNA1GCACNA1HTSHRRXRA | |
| SCHEMBL9989721 | 0.87 | MALT1 (0.56) | MALT1CACNA1GCACNA1HRXRARXRB | |
| SCHEMBL9990141 | 0.86 | RXRA (0.51) | MALT1RXRARXRBRXRGLMNA | |
| SCHEMBL9988567 | 0.85 | MALT1 (0.55) | MALT1RXRARXRBRXRGSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |