Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | RXRB | P28702 | 2/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RPA1 | P27694 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.46 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 2/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990141 | 0.96 | RXRA (0.51) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988567 | 0.95 | MALT1 (0.55) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988490 | 0.93 | LMNA (0.49) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9989011 | 0.92 | RXRA (0.48) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988536 | 0.92 | RXRA (0.48) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9989355 | 0.92 | MALT1 (0.62) | MALT1RXRARXRBRXRGTSHR | |
| SCHEMBL9988463 | 0.92 | RXRA (0.54) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988534 | 0.91 | MALT1 (0.55) | MALT1RXRARXRBRXRGLMNA | |
| SCHEMBL9988512 | 0.91 | MALT1 (0.57) | MALT1RXRARXRBRXRGTP53 | |
| SCHEMBL9988527 | 0.91 | RXRA (0.48) | MALT1RXRARXRBRXRGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |