Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990038 | 0.76 | SIGMAR1 (0.34) | SIGMAR1CHRM5CHRM3 | |
| SCHEMBL9989678 | 0.76 | KMT2A (0.43) | KMT2ASIGMAR1SLC6A4SMN1; SMN2HIF1A | |
| SCHEMBL4558755 | 0.75 | SIGMAR1 (0.45) | KMT2ASIGMAR1SLC6A4SMN1; SMN2HIF1A | |
| SCHEMBL9989667 | 0.74 | KMT2A (0.44) | KMT2ASIGMAR1SLC6A4SLC6A2OPRD1 | |
| SCHEMBL27527991 | 0.71 | SIGMAR1 (0.44) | KMT2ASIGMAR1SLC6A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL16054551 | 0.70 | KMT2A (0.40) | KMT2ASIGMAR1SLC6A4SMN1; SMN2HIF1A | |
| SCHEMBL29155320 | 0.69 | SIGMAR1 (0.45) | KMT2ASIGMAR1HTR6 | |
| SCHEMBL5607442 | 0.68 | HIF1A (0.47) | KMT2ASMN1; SMN2HIF1AALDH1A1CYP3A4 | |
| SCHEMBL4763928 | 0.68 | SIGMAR1 (0.50) | KMT2ASIGMAR1SLC6A4HIF1AALDH1A1 | |
| SCHEMBL1208824 | 0.68 | CHRM2 (0.47) | KMT2ASIGMAR1SLC6A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |