Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990034 | 0.77 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL9989678 | 0.74 | KMT2A (0.43) | KMT2ASIGMAR1SLC6A4OPRD1HTR6 | |
| SCHEMBL9989672 | 0.74 | KMT2A (0.43) | KMT2ASIGMAR1SLC6A4SLC6A2OPRD1 | |
| SCHEMBL665673 | 0.74 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL6803588 | 0.73 | HDAC3 (0.50) | KMT2ASSTR4SLC6A3GRM2GRM3 | |
| SCHEMBL4558755 | 0.73 | SIGMAR1 (0.45) | KMT2ASIGMAR1SLC6A4SLC6A2OPRD1 | |
| SCHEMBL4899599 | 0.72 | CHRM3 (0.40) | KMT2ASIGMAR1OPRD1 | |
| SCHEMBL9190217 | 0.71 | GRM2 (0.46) | KMT2ASSTR4SLC6A2SLC6A3GRM2 | |
| SCHEMBL5320849 | 0.71 | MAPT (0.46) | KMT2ASSTR4SLC6A2SLC6A3GRM2 | |
| SCHEMBL27957913 | 0.71 | AR (0.47) | KMT2ASSTR4SLC6A3GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |