Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518220 | 1.00 | MAPT (0.67) | MAPTALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL232188 | 0.91 | MAPT (0.78) | MAPTALDH1A1L3MBTL1TDP1DRD4 | |
| SCHEMBL8972676 | 0.89 | ALDH1A1 (0.60) | MAPTALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL10548798 | 0.89 | ALDH1A1 (0.54) | MAPTALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL1937279 | 0.89 | ALDH1A1 (0.60) | MAPTALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL1562142 | 0.88 | MAPT (0.74) | MAPTALDH1A1L3MBTL1TDP1DRD4 | |
| SCHEMBL6416019 | 0.88 | MAPT (0.74) | MAPTALDH1A1L3MBTL1TDP1DRD4 | |
| Bromide SCHEMBL8828468 | 0.87 | MAPT (0.52) | MAPTALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL30305695 | 0.87 | L3MBTL1 (0.73) | MAPTALDH1A1L3MBTL1SIGMAR1CA12 | |
| SCHEMBL8346697 | 0.85 | MAPT (0.56) | MAPTALDH1A1L3MBTL1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456795-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | claimed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | claimed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | claimed |
| EP-2456795-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| US-8153544-B2 | Method for preparing non-metallocene catalysts | EQUISTAR CHEMICALS, LP (US) | 2012-04-10 | — | — | US | disclosed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20040030093-A1 | Metal catalyst for ring-opening polymerization of heterocyclic compound | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| US-4179469-A | Preparation of amines | UOP INC. (US) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030093-A1 | Metal catalyst for ring-opening polymerization of heterocyclic compound | MAX, PCNA, POLM | MAPT 2518/4885ALDH1A1 2856/4885L3MBTL1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.