Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 7/20 | 0.53 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | CHKB | Q9Y259 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043798 | 0.83 | CHKA (0.40) | CHKALTC4SCSF1RKDM4EMAPT | |
| SCHEMBL13509013 | 0.81 | MEN1 (0.40) | CHKALMNAMAPTKMT2A | |
| SCHEMBL3524418 | 0.80 | GAA (0.59) | CHKACSF1RCHKBKDM4ELMNA | |
| SCHEMBL28000888 | 0.79 | CHKA (0.50) | CHKACSF1RCHKBKDM4ELMNA | |
| SCHEMBL29120709 | 0.78 | TSHR (0.40) | CHKALTC4SKDM4ELMNAMAPT | |
| SCHEMBL3261175 | 0.76 | CHKA (0.51) | CHKACSF1RCHKBKDM4ELMNA | |
| SCHEMBL6423587 | 0.76 | CHKA (0.51) | CHKACSF1RCHKBKDM4ELMNA | |
| SCHEMBL20210149 | 0.76 | RXRA (0.40) | CHKACSF1RGAAKMT2A | |
| SCHEMBL11105220 | 0.76 | ALDH1A1 (0.49) | CHKALTC4SCSF1RCHKBKDM4E | |
| SCHEMBL8233668 | 0.76 | KMT2A (0.57) | KDM4EGAAKMT2AGPBAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613504-A1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | Johnson Matthey Public Limited Company (GB) | 2020-02-26 | — | — | EP | disclosed |
| EP-3613504-A1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | Johnson Matthey Public Limited Company (GB) | 2020-02-26 | — | — | EP | disclosed |
| EP-2585216-B1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | JOHNSON MATTHEY PLC (GB) | 2019-11-20 | — | — | EP | disclosed |
| EP-2585216-B1 | PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS | JOHNSON MATTHEY PLC (GB) | 2019-11-20 | — | — | EP | disclosed |
| US-20190016742-A1 | Complexes | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-17 | — | — | US | disclosed |
| US-10167305-B2 | Allyl complexes for use in coupling reactions | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-01 | — | — | US | disclosed |
| US-10167305-B2 | Allyl complexes for use in coupling reactions | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-01 | — | — | US | disclosed |
| US-20130165660-A1 | COMPLEXES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-06-27 | — | — | US | disclosed |
| US-20130165660-A1 | COMPLEXES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-06-27 | — | — | US | disclosed |
| US-20130165660-A1 | COMPLEXES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-06-27 | — | — | US | disclosed |
| EP-2585216-A1 | COMPLEXES | Johnson Matthey PLC (GB) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011161451-A1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011161451-A1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2011-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167305-B2 | Allyl complexes for use in coupling reactions | AP3M1, AP1M1, C9 | CHKA 3356/4885LTC4S 1532/4885CSF1R 1126/4885 |
| US-20190016742-A1 | Complexes | C5, C1S, C9 | CHKA 3990/4885LTC4S 1873/4885CSF1R 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.