SCHEMBL9993152

SCHEMBL9993152

Oc1c(Cl)cc(Cl)cc1CBr

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.56
ALDH1A1 P00352 4/20 0.56
CYP3A4 P08684 3/20 0.56
TSHR P16473 3/20 0.56
RECQL P46063 2/20 0.56
HSP90AA1 P07900 1/20 0.53
CYP1A2 P05177 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 2/20 0.50
PRMT1 Q99873 1/20 0.50
CYP2D6 P10635 1/20 0.50
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
HPGD P15428 4/20 0.45
LMNA P02545 3/20 0.45
HIF1A Q16665 3/20 0.45
HTT P42858 2/20 0.45
MAPT P10636 2/20 0.45
POLB P06746 2/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29516784 0.88 HIF1A (0.48) HSD17B10ALDH1A1CYP3A4TSHRRECQL
Bromide SCHEMBL6440480 0.86 HIF1A (0.47) HSD17B10ALDH1A1CYP3A4TSHRRECQL
Bromide SCHEMBL6440482 0.86 HIF1A (0.47) HSD17B10ALDH1A1CYP3A4TSHRRECQL
SCHEMBL11505512 0.81 HSD17B10 (0.62) HSD17B10ALDH1A1CYP3A4TSHRRECQL
SCHEMBL67608 0.81 HSP90AA1 (0.74) HSD17B10ALDH1A1CYP3A4TSHRRECQL
SCHEMBL23434900 0.81 CYP3A4 (0.50) HSD17B10ALDH1A1CYP3A4TSHRRECQL
SCHEMBL11591823 0.80 ERN1 (0.47) HSD17B10ALDH1A1CYP3A4TSHRRECQL
SCHEMBL11590889 0.80 TSHR (0.37) HSD17B10ALDH1A1CYP3A4TSHRRECQL
SCHEMBL28903722 0.79 HSD17B10 (0.59) HSD17B10ALDH1A1CYP3A4TSHRRECQL
SCHEMBL29577605 0.79 HSD17B10 (0.59) HSD17B10ALDH1A1CYP3A4TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462720-A Aminophenoxy transition metal complex and preparation method and application thereof 万华化学集团股份有限公司 2025-02-18 CN disclosed
CN-119060314-A Polymerization method of beta-butyrolactone 华东理工大学 2024-12-03 CN disclosed
CN-108558932-B Bis (2-pyridyl) methyl-substituted aminophenoxy magnesium complex and preparation method and application thereof 华东理工大学 2022-10-25 CN disclosed
EP-3126325-B1 PHENYLENE-BRIDGED SALALEN CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-04-24 EP disclosed
EP-3126325-B1 PHENYLENE-BRIDGED SALALEN CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-04-24 EP disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
EP-3126325-A1 PHENYLENE-BRIDGED SALALEN CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2017-02-08 EP disclosed
US-9493587-B2 Metal complexes of salan-type ligands and uses thereof as catalysts for polymerization of alpha-olefins RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2016-11-15 US disclosed
EP-2582710-B1 SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES UNIV RAMOT (IL) 2016-08-10 EP disclosed
US-20130059991-A1 CATALYST FOR STEREOSELECTIVE OLEFIN POLYMERIZATION AND METHOD FOR MANUFACTURING STEREOSELECTIVE POLYOLEFIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-07 US disclosed
US-20130059991-A1 CATALYST FOR STEREOSELECTIVE OLEFIN POLYMERIZATION AND METHOD FOR MANUFACTURING STEREOSELECTIVE POLYOLEFIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-07 US disclosed
US-20130041119-A1 OLEFIN POLYMER PRODUCING METHOD, ETHYLENE POLYMER, AND MOLD PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-14 US disclosed
US-20130041119-A1 OLEFIN POLYMER PRODUCING METHOD, ETHYLENE POLYMER, AND MOLD PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-14 US disclosed
US-20130035462-A1 ETHYLENIC POLYMERIZATION CATALYST AND METHOD FOR MANUFACTURING ETHYLENIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 US disclosed
US-20130035462-A1 ETHYLENIC POLYMERIZATION CATALYST AND METHOD FOR MANUFACTURING ETHYLENIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 US disclosed
WO-2012098521-A1 METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2012-07-26 WO disclosed
WO-2011158241-A1 SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2011-12-22 WO disclosed
US-4113777-A ANTISECRETORY, ANTITUSSIVE, ANTIULCER BOEHRINGER INGELHEIM GMBH (DE) 1978-09-12 US disclosed
US-4073942-A Halo-substituted hydroxybenzyl-amines as secretolytic agents BOEHRINGER INGELHEIM GMBH (DT) 1978-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035462-A1 ETHYLENIC POLYMERIZATION CATALYST AND METHOD FOR MANUFACTURING ETHYLENIC POLYMER EPB41, ELOVL6, ELOVL5 HSD17B10 766/4885ALDH1A1 2084/4885CYP3A4 38/4885
US-20130059991-A1 CATALYST FOR STEREOSELECTIVE OLEFIN POLYMERIZATION AND METHOD FOR MANUFACTURING STEREOSELECTIVE POLYOLEFIN OR10J3, ORMDL3, OGFRL1 HSD17B10 1255/4885ALDH1A1 2762/4885CYP3A4 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.